Manchester United will face Spanish side Celta Vigo in the semi-finals of the Europa League. United have never played the Spanish team before in any competition but will consider themselves in the driving seat against a Celta side mid-table in La Liga.
Jose Mourinho's men play the first leg at Balaidos on May 4 with the return leg at Old Trafford on May 11.
In the other semi-final dutch side Ajax Amsterdam, winners in 1992, come up against French club Olympique Lyon in the other last-four tie.
The first legs will be played on 4 May with the second leg on 11 May, and the final in Stockholm, Sweden on 24 May.
Red devils manager Jose Mourinho won the competition with FC Porto in 2003
The Premier League side Man United have won the European Cup three times but have never triumphed in the continent's secondary club competition.
Ajax, who beat Germans Schalke, 4-3 on aggregate to reach the last four, are also experienced European campaigners. They have won the Champions League/European Cup four times previously and the Europa League/Uefa Cup once, beating Torino in the 1992 final.